Jarrow Formulas, SAM-e 400 mg, 30 Enteric-Coated Tablets

SAM-e ( S-Adenosyl Methionine )
Longevity, Joint Strength, Liver Detoxification, Mood and Brain Function

• S-Adenosyl Methionine Full Potency
• Pharmaceutical Grade, Stabilized
• Highest Concentration of Active S, S Form

Jarrow Formulas SAM-e 400 pharmaceutical grade, stabilized SAM-e is a full 400 mg elemental SAM-e from 800 mg of SAM-e tosylate disulfate. S-Adenosyl Methionine is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product.

Contains More of the Active S, S Form.

SAM-e (S-Adenosyl Methionine) is a chiral molecule and therefore consists of two forms: (S,S) SAM-e and (R,S) SAM-e. The biologically active form is the (S,S) structure, while the (R,S) structure is biologically inactive.

Jarrow Formulas S-Adenosyl Methionine is made naturally by microbiological fermentation and then specially processed to preserve 68-80% (S,S) SAM-e the highest active level available. SAM-e is an amino acid derivative that has been clinically proven to benefit brain, joint and liver function. Found in all living cells, SAM-e is also called "activated" methionine (an essential amino acid) since it is formed by the combining of ATP with methionine. SAM-e has undergone dozens of trials involving thousands of patients. Researchers studying the beneficial effects of SAM-e have identified the following benefits of SAM-e:

• Joint Strength - SAM-e supports the production of healthy connective tissue through transulfuration. In this process, critical components of connective tissue, including glucosamine and the chondroiton sulfates, are sulfated by SAM-e metabolites.
• Brain Metabolism - SAM-e methylation reactions are involved in the synthesis of neurotransmitters such as L-dopa, dopamine and related hormones, epinephrine and phosphatidulcholine (a component of lecithin).
• Longevity - Methylation of DNA appears to be important in the suppression of errors in DNA replication. Demthylation of DNA is considered a contributor to the aging process. Proper methylation through substances such as SAM-e positively influences longevity.
  
• Liver - SAM-e metabolism supports the synthesis of glutathione (GSH) and glutathionine-dependent enzymes (glutathionine peroxidase and glutathionie-S-transferase), which are substances important for liver function.
  

Supplement Facts
Serving Size 1 Tablet
Amount Per Tablet %DV
S-Adenosyl Methionine 400 mg
(from 800 mg of SAM-e tosylate disulfate)

Other Ingredients: Enteric coating (methacrylate copolymers), microcrstalline cellulose, mannitol, sodium starch glyconate, silicon dioxide, glycerol behenate, magnesium stearate, titanium dioxide, magnesium silicate, triethyl citrate, and yellow ochre.

Jarrow Formulas' SAM-e 400 is foil blister-packed to maximize stability and safety. Do not use if outer seal of blister pack is broken.

Directions
Take 1 to 2 tablets per day on an empty stomach, or as directed by your qualified health consultant.

Warning: Individuals using prescribed medications such as antidepressants, including Serotonin Re-Uptake Inhibitors should consult a physician before using. Individuals with bi-polar disorder or manic depression should not use SAM-e.